Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433832 | 0.81 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL15228092 | 0.81 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL15125011 | 0.81 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL2456548 | 0.81 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL6691407 | 0.80 | CYP1A2 (0.48) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL6688205 | 0.80 | CYP1A2 (0.48) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL19746429 | 0.80 | TSHR (0.44) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL28689277 | 0.79 | CYP1A2 (0.52) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL5925077 | 0.78 | CYP1A2 (0.50) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 | |
| SCHEMBL27466589 | 0.78 | CYP1A2 (0.50) | CYP1A2TSHRALDH1A1HIF1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072580-B1 | PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID | IHARA CHEMICAL IND CO (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-7491834-B2 | Chemical process | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20060163159-A1 | Chemical process | SYNGENTA CROP PROTECTION, INC. | 2006-07-27 | — | — | US | disclosed |
| CN-1226294-C | Fused heteroaromatic glucokinase activators | HOFFMANN LA ROCHE (CH) | 2005-11-09 | — | — | CN | disclosed |
| US-20050119252-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| WO-2005042516-A2 | LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-1506184-A2 | PROCESS FOR THE PREPARATION OF 3-ISOCHROMANONE | Syngenta Limited (GB) | 2005-02-16 | — | — | EP | disclosed |
| CN-1476438-A | Fused heteroaromatic glucokinase activators | - | 2004-02-18 | — | — | CN | disclosed |
| WO-2003095442-A2 | PROCESS FOR THE PREPARATION OF 3-ISOCHROMANONE | SYNGENTA LIMITED (GB) | 2003-11-20 | — | — | WO | disclosed |
| US-6414186-B1 | REACTING METHYLPHENYLACETIC ACID WITH CHLORINE GAS, IN INERT SOLVENT, UNDER IRRADIATION WITH LIGHT OR IN PRESENCE OF RADICAL INITIATOR | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1072580-A1 | PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID | Ihara Nikkei Chemical Industry Co., Ltd. (JP) | 2001-01-31 | — | — | EP | disclosed |
| EP-0593559-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. (GB) | 1994-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119252-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | MC3R, MC1R, MC4R | CYP1A2 1024/4885TSHR 55/4885ALDH1A1 2864/4885 |
| US-20060163159-A1 | Chemical process | HAO2, OGDH, TST | CYP1A2 270/4885TSHR 559/4885ALDH1A1 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.