SCHEMBL2456583

SCHEMBL2456583

Cc1c(O)ccc(C(=O)OO)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
HSD17B10 Q99714 1/20 0.42
CA12 O43570 8/20 0.38
CA1 P00915 8/20 0.38
CA2 P00918 8/20 0.38
CA7 P43166 8/20 0.38
CA9 Q16790 8/20 0.38
CA14 Q9ULX7 8/20 0.38
PDK2 Q15119 1/20 0.37
PDK4 Q16654 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
CSNK2A1 P68400 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28760512 0.89 TSHR (0.38) MEN1KMT2ANPC1ALDH1A1HTT
SCHEMBL5589044 0.86 MEN1 (0.43) MEN1KMT2ANPC1ALDH1A1HTT
SCHEMBL733030 0.83 CA1 (0.55) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL2706734 0.82 TSHR (0.47) MEN1KMT2ANPC1ALDH1A1HTT
SCHEMBL28455094 0.81 POLB (0.35) MEN1KMT2ANPC1ALDH1A1HTT
SCHEMBL311150 0.81 CYP1A2 (0.42) ALDH1A1HSD17B10LMNATSHRCSNK2A1
SCHEMBL29266102 0.80 CA12 (0.61) MEN1KMT2AALDH1A1RAB9AHSD17B10
SCHEMBL5952738 0.78 KDM4E (0.46) MEN1KMT2ANPC1ALDH1A1HTT
SCHEMBL4132989 0.78 NPC1 (0.42) MEN1KMT2ANPC1ALDH1A1HTT
SCHEMBL28401729 0.76 NR1H4 (0.35) MEN1KMT2ANPC1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2368602-A1 Deodorant perfume composition comprising essential oils for masking an acid odour Takasago International Corporation (JP) 2011-09-28 EP disclosed