SCHEMBL311150

SCHEMBL311150

Cc1c(C(=O)O)ccc(C(=O)OO)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
ALDH1A1 P00352 5/20 0.40
TSHR P16473 2/20 0.39
KDM4E B2RXH2 3/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
HAAO P46952 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
GABRA4 P48169 1/20 0.38
GABRE P78334 1/20 0.38
GABRA6 Q16445 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28760512 0.91 TSHR (0.38) CYP1A2ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL128319 0.83 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL31389208 0.83 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL2004816 0.83 CA12 (0.47) CYP1A2ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL28455094 0.83 POLB (0.35) ALDH1A1TSHRHPGDLMNA
SCHEMBL18204383 0.81 RAB9A (0.39) CYP1A2ALDH1A1TSHRKDM4EGABRP
Ammonia Solution, Strong SCHEMBL29137499 0.81 CYP1A2 (0.55) CYP1A2ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL2456583 0.81 MEN1 (0.44) ALDH1A1TSHRHSD17B10LMNACSNK2A1
SCHEMBL7576792 0.81 ALDH1A1 (0.43) CYP1A2ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL10871292 0.81 CYP1A2 (0.41) CYP1A2ALDH1A1TSHRKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103384673-B Hyperbranched oligomeric phosphonate and include the compositions of described hyperbranched oligomeric phosphonate FRX聚合物股份有限公司 2016-08-31 CN claimed
CN-103384673-A Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS INC 2013-11-06 CN claimed
EP-2655383-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
US-8530044-B2 Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-09-10 US claimed
US-20120171460-A1 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US claimed
WO-2012088435-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
US-20110144266-A1 Thermoplastic Articles Comprising Cyclobutanediol Having a Decorative Material Embedded Therein EASTMAN CHEMICAL COMPANY (US) 2011-06-16 US claimed
US-7906212-B2 Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein EASTMAN CHEMICAL COMPANY (US) 2011-03-15 US claimed
US-7906211-B2 Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein EASTMAN CHEMICAL COMPANY (US) 2011-03-15 US claimed
US-20100174033-A1 THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2010-07-08 US claimed
EP-1575774-A1 ARTICLES OF MANUFACTURE INCORPORATING POLYESTER/POLYCARBONATE BLENDS EASTMAN CHEMICAL COMPANY (US) 2005-09-21 EP claimed
EP-1569795-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2005-09-07 EP claimed
US-6896966-B2 Articles of manufacture incorporating polyester/polycarbonate blends EASTMAN CHEMICAL COMPANY (US) 2005-05-24 US claimed
WO-2004048090-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2004-06-10 WO claimed
WO-2004048089-A1 ARTICLES OF MANUFACTURE INCORPORATING POLYESTER/POLYCARBONATE BLENDS EASTMAN CHEMICAL COMPANY (US) 2004-06-10 WO claimed
US-20040101678-A1 Thermoplastic article having a decorative material embedded therein EASTMAN CHEMICAL COMPANY 2004-05-27 US claimed
US-20040101687-A1 Articles of manufacture incorporating polyester/polycarbonate blends EASTMAN CHEMICAL COMPANY 2004-05-27 US claimed
EP-0708792-A1 PREPARATION OF BRANCHED POLYETHYLENE TEREPHTHALATE EASTMAN CHEMICAL COMPANY (US) 1996-05-01 EP claimed
WO-1995002623-A1 PREPARATION OF BRANCHED POLYETHYLENE TEREPHTHALATE EASTMAN CHEMICAL COMPANY (US) 1995-01-26 WO claimed
US-5376735-A Preparation of branched polyethylene terephthalate EASTMAN CHEMICAL COMPANY (US) 1994-12-27 US claimed