Methyl Nicotinate

Methyl Nicotinate

SCHEMBL24566

COC(=O)c1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
KMT2A Q03164 6/20 0.67
HSD17B10 Q99714 1/20 0.60
APP P05067 1/20 0.59
GAA P10253 1/20 0.59
HCAR3 P49019 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
HDAC1 Q13547 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
TSHR P16473 1/20 0.57
F7 P08709 1/20 0.57
F3 P13726 1/20 0.57
SARM1 Q6SZW1 1/20 0.57
SIRT2 Q8IXJ6 1/20 0.57
SIRT6 Q8N6T7 1/20 0.57
SIRT1 Q96EB6 1/20 0.57
SIRT3 Q9NTG7 1/20 0.57
SIRT5 Q9NXA8 1/20 0.57
SIRT4 Q9Y6E7 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Nicotinate SCHEMBL29386553 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL820747 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL30668199 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL30541951 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL28370871 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL29527047 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL11491005 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL30779127 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL30791985 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA
Methyl Nicotinate SCHEMBL3086138 0.98 ALDH1A1 (0.96) ALDH1A1KMT2AHSD17B10APPGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6637 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117409-A1 COMPOSITION FOR PLATING METAL COATINGS AND METHODS OF MAKING AND USING THE SAME BATTELLE MEMORIAL INSTITUTE (US) 2026-04-30 US claimed
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
US-12583860-B2 Processes for the preparation of multicomponent crystalline forms of active pharmaceutical ingredients using solvent vapour APOTEX INC. (CA) 2026-03-24 US claimed
EP-4687829-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2026-02-11 EP claimed
US-20260035302-A1 Concrete Composition with Corrosion Inhibitor VISCO JR DONALD P (US) 2026-02-05 US claimed
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-18 US claimed
US-12485134-B2 Use of nicotinamide riboside, nicotinic acid riboside, reduced nicotinyl riboside compounds, and nicotinyl riboside compound derivatives in formulations ChromaDex Inc. (US) 2025-12-02 US claimed
US-20250345299-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF T OMEGA AS (NO) 2025-11-13 US claimed
US-20250302368-A1 Wearable Device For Skin Testing SHANGHAI TIANYIN BIOLOGICAL TECHNOLOGY CO., LTD. (CN) 2025-10-02 US claimed
US-20250268841-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2025-08-28 US claimed
EP-0233287-A1 1,4-THIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND CARDIOTONICS CONTAINING THE SAME ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 1987-08-26 EP claimed
EP-0225848-A2 Analgesic stick composition WARNER-LAMBERT COMPANY (US) 1987-06-16 EP claimed
US-4634687-A COCATALYST FOR COORDINATION CATALYST TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1987-01-06 US claimed
US-4625021-A High yield process for preparing beta-lactam antibiotics having a high purity degree ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. (IT) 1986-11-25 US claimed
CN-86100224-A The preparation method of psycholeptic 2-(4-butyl piperazine-1-yl) pyridines cyclic imide derivative 1986-11-19 CN claimed
EP-0095341-B1 PENICILLANIC ACID DIOXIDE PRODRUG PFIZER INC. (US) 1986-02-26 EP claimed
US-4563446-A ANTICOAGULANT, ANTISCHEMIC TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-01-07 US claimed
EP-0126684-A2 Drug delivery system utilizing thermosetting gels MERCK & CO. INC. (US) 1984-11-28 EP claimed
EP-0095341-A1 Penicillanic acid dioxide prodrug PFIZER INC. (US) 1983-11-30 EP claimed
US-4217408-A GELATIN OR NITROCELLULOSE INTERLAYER, HYDROPHILIC DIFFUSION TRANSFER IMAGE RECEIVING LAYER FUJI PHOTO FILM CO., LTD. (JP) 1980-08-12 US claimed