Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494433 | 0.96 | PTPN11 (0.50) | PTPN11GCGRNPC1RAB9AUNG | |
| SCHEMBL14354863 | 0.89 | CYP2D6 (0.51) | PTPN11GCGRCYP2D6CYP3A4NPC1 | |
| SCHEMBL17485686 | 0.84 | PTPN11 (0.49) | PTPN11GCGRCYP2D6CYP3A4NPC1 | |
| SCHEMBL19157196 | 0.84 | PTPN11 (0.46) | PTPN11GCGRCYP2D6CYP3A4NPC1 | |
| SCHEMBL25852886 | 0.83 | PTPN11 (0.54) | PTPN11CYP2D6CYP3A4CYP1A2CYP19A1 | |
| SCHEMBL14231474 | 0.82 | MEN1 (0.51) | PTPN11GCGRCYP2D6CYP3A4NPC1 | |
| SCHEMBL21670573 | 0.81 | CYP2D6 (0.40) | PTPN11GCGRCYP2D6CYP3A4NPC1 | |
| SCHEMBL30525977 | 0.81 | CYP2D6 (0.40) | PTPN11GCGRCYP2D6CYP3A4NPC1 | |
| SCHEMBL24727509 | 0.81 | PTPN11 (0.52) | PTPN11GCGRTHRB | |
| SCHEMBL21670599 | 0.80 | PTPN11 (0.42) | PTPN11GCGRCYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019522-B1 | NEW DERIVATIVES OF PYRROLOPYRROLE CYANINES AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022144228-A1 | NEW DERIVATIVES OF PYRROLOPYRROLE CYANINES AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-07-07 | — | — | WO | disclosed |
| EP-4019522-A1 | NEW DERIVATIVES OF PYRROLOPYRROLE CYANINES AND USES THEREOF | Centre national de la recherche scientifique (FR) | 2022-06-29 | — | — | EP | disclosed |