Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354863 | 0.95 | CYP2D6 (0.51) | PTPN11CYP2D6CYP3A4MEN1ALDH1A1 | |
| SCHEMBL18311338 | 0.91 | GAA (0.48) | PTPN11CYP2D6CYP3A4NR1I2MEN1 | |
| SCHEMBL25852886 | 0.89 | PTPN11 (0.54) | PTPN11CYP2D6CYP3A4LTA4HNR5A1 | |
| SCHEMBL17485690 | 0.87 | MCL1 (0.46) | PTPN11CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL19157196 | 0.87 | PTPN11 (0.46) | PTPN11CYP2D6CYP3A4MEN1ALDH1A1 | |
| SCHEMBL17488401 | 0.85 | L3MBTL1 (0.41) | PTPN11CYP3A4NR1I2ALDH1A1L3MBTL1 | |
| SCHEMBL24566635 | 0.84 | PTPN11 (0.44) | PTPN11CYP2D6CYP3A4MEN1ALDH1A1 | |
| SCHEMBL14231474 | 0.84 | MEN1 (0.51) | PTPN11CYP2D6CYP3A4MEN1ALDH1A1 | |
| SCHEMBL20928533 | 0.84 | PTPN11 (0.47) | PTPN11CYP2D6CYP3A4NPC1RAB9A | |
| SCHEMBL30504182 | 0.84 | PTPN11 (0.47) | PTPN11CYP2D6CYP3A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124465-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-02-01 | — | — | EP | disclosed |
| US-20160032189-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | US | disclosed |
| EP-2980062-A2 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-9023656-B2 | Reactive mass labels | ELECTROPHORETICS LIMITED (GB) | 2015-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160032189-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, ILK, LCP1 | PTPN11 770/4885CYP2D6 2575/4885CYP3A4 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.