Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614311 | 0.86 | ACACB (0.52) | ACACBKMT2APIK3CDABL1HDAC1 | |
| SCHEMBL24568381 | 0.80 | ACACB (0.55) | ACACBKMT2AKIF11 | |
| SCHEMBL1992633 | 0.79 | KMT2A (0.49) | ACACBKMT2AABL1HDAC1KIF11 | |
| SCHEMBL24567564 | 0.78 | ACACB (0.53) | ACACBKMT2APIK3CDHDAC1TAS1R3 | |
| SCHEMBL2780654 | 0.76 | — | — | |
| SCHEMBL343489 | 0.76 | — | — | |
| SCHEMBL30565167 | 0.75 | ACACB (0.62) | ACACB | |
| SCHEMBL3425315 | 0.75 | — | — | |
| SCHEMBL5140577 | 0.75 | KMT2A (0.51) | ACACBKMT2APIK3CDABL1CSF1R | |
| Hydrochloric Acid SCHEMBL23411737 | 0.74 | KMT2A (0.51) | ACACBKMT2APIK3CDABL1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |