⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23411737 | 0.98 | KMT2A (0.51) | — | |
| SCHEMBL3425315 | 0.83 | — | — | |
| Glyphosate SCHEMBL5075104 | 0.80 | KMT2A (0.38) | — | |
| SCHEMBL2780654 | 0.79 | — | — | |
| SCHEMBL28187036 | 0.79 | — | — | |
| SCHEMBL21286901 | 0.79 | — | — | |
| SCHEMBL3456432 | 0.79 | KMT2A (0.49) | — | |
| SCHEMBL5140577 | 0.79 | KMT2A (0.51) | — | |
| SCHEMBL2614311 | 0.79 | ACACB (0.52) | — | |
| SCHEMBL14104367 | 0.79 | KMT2A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004228-B | GSK-3 beta/ChE double inhibitor and preparation method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | claimed |
| EP-3240421-A1 | MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH | FMC Corporation (US) | 2017-11-08 | — | — | EP | claimed |
| CN-106660975-A | 2-aryl-4-hydroxy-1, 3-thiazole derivatives as TRPM 8-inhibitors for the treatment of neuralgia, pain, COPD and asthma | 东佩制药股份公司 | 2017-05-10 | — | — | CN | claimed |
| WO-2016108972-A1 | MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH | FMC CORPORATION (US) | 2016-07-07 | — | — | WO | claimed |
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250236608-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-07-24 | — | — | US | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |
| US-20230141212-A1 | SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS | DICE ALPHA, INC. | 2023-05-11 | — | — | US | disclosed |
| EP-4175954-A1 | COMBINATION OF AN ALPHA2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONIST WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2023-05-10 | — | — | EP | disclosed |
| CN-110950843-B | Substituted benzamide derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| EP-2220939-A2 | Synergistic fungicidal combinations | Bayer CropScience AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2010023171-A2 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM | BASF SE (DE) | 2010-03-04 | — | — | WO | disclosed |
| US-20100029722-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
| EP-2029572-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20080261978-A1 | treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers; 1-(4-((pyridin-2-ylmethylamino)methyl)benzyl)-3-phenylurea | METASTATIX, INC. | 2008-10-23 | — | — | US | disclosed |
| WO-2007143597-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-12-13 | — | — | WO | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070060579-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |