Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848314 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1RAB9AMAPTADRA1A | |
| SCHEMBL24567555 | 0.82 | MAP3K5 (0.41) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL11823698 | 0.79 | MEN1 (0.83) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL13368482 | 0.78 | BRD4 (0.61) | KMT2ARAB9AADRA1ATSHRHTT | |
| SCHEMBL31186009 | 0.78 | GRN (0.48) | — | |
| SCHEMBL31186139 | 0.76 | CNR1 (0.49) | — | |
| SCHEMBL799662 | 0.74 | KMT2A (0.75) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2280624 | 0.73 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1RAB9AMAPTPOLB | |
| SCHEMBL23689650 | 0.73 | MEN1 (0.73) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL15204485 | 0.73 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |