SCHEMBL24568593

SCHEMBL24568593

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
KDM4E B2RXH2 2/20 0.40
ATM Q13315 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GGPS1 O95749 1/20 0.39
PRKDC P78527 7/20 0.39
PLA2G2A P14555 3/20 0.37
PLA2G4A P47712 3/20 0.37
PTGES2 Q9H7Z7 1/20 0.37
PLA2G10 O15496 1/20 0.36
PIK3CD O00329 2/20 0.35
PIK3CA P42336 2/20 0.35
PIK3CB P42338 2/20 0.35
PIK3CG P48736 2/20 0.35
PDE2A O00408 1/20 0.35
PIK3C2A O00443 1/20 0.35
PIK3R2 O00459 1/20 0.35
PIK3C2B O00750 1/20 0.35
BRD4 O60885 1/20 0.35
PDE5A O76074 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14212275 1.00 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL24810812 1.00 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL22329163 1.00 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL24173859 1.00 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL24810817 0.99 ALOX5 (0.47) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL20715160 0.98 ALOX5 (0.46) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL24811972 0.98 ALOX5 (0.46) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL16804071 0.98 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1GGPS1
SCHEMBL24173855 0.98 ALOX5 (0.50) ALOX5KDM4EATMGGPS1PRKDC
SCHEMBL24173853 0.98 ALOX5 (0.50) ALOX5KDM4EATMGGPS1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204673-A1 COPOLYMER, ELECTROLUMINESCENT DEVICE MATERIAL INCLUDING COPOLYMER, AND ELECTROLUMINESCENT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-06-30 US disclosed