Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897243 | 0.81 | CHRM2 (0.42) | HPGDGAA | |
| SCHEMBL4069968 | 0.79 | DPP4 (0.38) | LIPEHPGDGAA | |
| SCHEMBL17471258 | 0.79 | PIK3CD (0.49) | HPGDGAA | |
| SCHEMBL23408433 | 0.79 | PIK3CD (0.49) | HPGDGAA | |
| SCHEMBL21138354 | 0.79 | RAB9A (0.38) | HPGDGAA | |
| SCHEMBL13145213 | 0.78 | GAA (0.44) | ALDH1A1HPGDHTTHSD11B1GAA | |
| SCHEMBL23046551 | 0.78 | DPP4 (0.37) | HPGDGAA | |
| SCHEMBL10823297 | 0.78 | GAA (0.35) | ALDH1A1HPGDGAA | |
| SCHEMBL9671329 | 0.78 | GAA (0.35) | ALDH1A1HPGDGAA | |
| SCHEMBL13257207 | 0.76 | TSHR (0.50) | ALDH1A1HPGDCNR2HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |