Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760418 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APSEN1PSEN2 | |
| SCHEMBL18040923 | 0.83 | BCHE (0.43) | SMN1; SMN2NPC1RAB9ACTSLCTSB | |
| SCHEMBL439043 | 0.83 | GBA1 (0.44) | SMN1; SMN2NPC1RAB9ACTSLCTSB | |
| SCHEMBL441959 | 0.81 | BCHE (0.42) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL28760417 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9APSEN1PSEN2 | |
| SCHEMBL439892 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9APSEN1PSEN2 | |
| SCHEMBL18580306 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ACTSLCTSB | |
| SCHEMBL25302878 | 0.77 | TDP1 (0.40) | SMN1; SMN2NPC1RAB9ACTSLCTSB | |
| SCHEMBL21196194 | 0.77 | CTSL (0.40) | SMN1; SMN2NPC1RAB9ACTSLCTSB | |
| SCHEMBL30379975 | 0.77 | CTSL (0.40) | SMN1; SMN2NPC1RAB9ACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773854-B1 | AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF | SANOFI SA (FR) | 2011-09-21 | — | — | EP | disclosed |
| EP-1773854-A2 | AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF | Sanofi-Aventis (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006021653-A2 | AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |