Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24569015 | 1.00 | CYP2C19 (0.83) | CYP2C19HIF1AALDH1A1L3MBTL1MPO | |
| SCHEMBL9734270 | 0.93 | CYP2C19 (0.97) | CYP2C19HIF1AALDH1A1L3MBTL1MPO | |
| SCHEMBL20476290 | 0.91 | CYP2C19 (1.00) | CYP2C19HIF1AALDH1A1L3MBTL1MPO | |
| SCHEMBL9073236 | 0.88 | CYP2C19 (0.71) | CYP2C19HIF1AALDH1A1L3MBTL1TNKS | |
| SCHEMBL4902515 | 0.88 | CYP2C19 (0.71) | CYP2C19HIF1AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9532332 | 0.87 | CYP2C19 (0.66) | CYP2C19HIF1AALDH1A1L3MBTL1TNKS | |
| SCHEMBL24568974 | 0.85 | CYP2C19 (0.68) | CYP2C19HIF1AALDH1A1L3MBTL1MPO | |
| SCHEMBL9975979 | 0.82 | CYP2C19 (0.58) | CYP2C19HIF1AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL18118439 | 0.81 | CYP2C19 (0.57) | CYP2C19HIF1AALDH1A1L3MBTL1TNKS | |
| SCHEMBL24569273 | 0.80 | CYP2C19 (0.60) | CYP2C19HIF1AALDH1A1L3MBTL1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492340-B2 | Heteroaromatic electrophiles and methods of using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220204472-A1 | HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492340-B2 | Heteroaromatic electrophiles and methods of using thereof | ACHE, BCHE, CHAT | CYP2C19 1082/4885HIF1A 4647/4885ALDH1A1 1025/4885 |
| US-20220204472-A1 | HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF | ACHE, BCHE, CHAT | CYP2C19 1082/4885HIF1A 4647/4885ALDH1A1 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.