Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248975 | 1.00 | AOC3 (0.34) | AOC3EGFRNPBWR1 | |
| SCHEMBL24573427 | 0.87 | EGFR (0.33) | EGFR | |
| SCHEMBL29734357 | 0.87 | EGFR (0.33) | EGFR | |
| SCHEMBL29735018 | 0.85 | AKT1 (0.33) | EGFR | |
| SCHEMBL24573623 | 0.85 | AKT1 (0.33) | EGFR | |
| SCHEMBL24573607 | 0.85 | NPBWR1 (0.35) | AOC3EGFRNPBWR1 | |
| SCHEMBL24573580 | 0.83 | NPBWR1 (0.35) | NPBWR1 | |
| SCHEMBL30248958 | 0.82 | NPBWR1 (0.34) | EGFRNPBWR1 | |
| SCHEMBL24573583 | 0.82 | NPBWR1 (0.34) | EGFRNPBWR1 | |
| SCHEMBL24573302 | 0.81 | EGFR (0.34) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022137085-A1 | INDOLE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | NOVARTIS AG (CH) | 2022-06-30 | — | — | WO | disclosed |