Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29735094 | 1.00 | NPBWR1 (0.34) | NPBWR1PDE10AFLT3 | |
| SCHEMBL24572591 | 0.92 | PDE10A (0.32) | NPBWR1PDE10AFLT3 | |
| SCHEMBL24573369 | 0.87 | NPBWR1 (0.36) | NPBWR1 | |
| SCHEMBL24572592 | 0.86 | NPBWR1 (0.36) | NPBWR1 | |
| SCHEMBL30248872 | 0.86 | NPBWR1 (0.36) | NPBWR1 | |
| SCHEMBL30248961 | 0.85 | NPBWR1 (0.35) | NPBWR1 | |
| SCHEMBL24573133 | 0.85 | NPBWR1 (0.35) | NPBWR1 | |
| SCHEMBL29735025 | 0.83 | NPBWR1 (0.34) | NPBWR1 | |
| SCHEMBL24572593 | 0.83 | NPBWR1 (0.34) | NPBWR1 | |
| SCHEMBL24573636 | 0.83 | NPBWR1 (0.35) | NPBWR1PDE10AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022137085-A1 | INDOLE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | NOVARTIS AG (CH) | 2022-06-30 | — | — | WO | disclosed |