SCHEMBL2457396

SCHEMBL2457396

CCCCCCCOc1ccccc1C(=O)Oc1ccccc1OC(=O)c1ccccc1OCCCCCCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.70
CYP3A4 P08684 2/20 0.70
MAPT P10636 2/20 0.70
KMT2A Q03164 2/20 0.70
MEN1 O00255 1/20 0.70
NR1I2 O75469 1/20 0.70
CHRM2 P08172 1/20 0.70
ADRA2A P08913 1/20 0.70
OPRK1 P41145 1/20 0.70
HTR2B P41595 1/20 0.70
SLC6A3 Q01959 1/20 0.70
HDAC6 Q9UBN7 1/20 0.70
TSHR P16473 3/20 0.59
ALDH1A1 P00352 3/20 0.59
PTPN11 Q06124 2/20 0.58
TP53 P04637 1/20 0.57
MAPK1 P28482 1/20 0.57
NPSR1 Q6W5P4 1/20 0.56
KDM4E B2RXH2 1/20 0.52
POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7588539 1.00 LMNA (0.70) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL28459314 0.94 LMNA (0.66) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL10619583 0.91 LMNA (0.63) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL17845808 0.91 KMT2A (0.63) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL9163993 0.91 KMT2A (0.63) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL2457395 0.91 LMNA (0.67) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL5472078 0.90 LMNA (0.62) LMNACYP3A4MAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL5472083 0.90 KMT2A (0.62) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL2169334 0.90 LMNA (0.65) LMNACYP3A4MAPTKMT2AMEN1
SCHEMBL5962507 0.90 LMNA (0.65) LMNACYP3A4MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0803525-A2 Chiral anisotropic thermosets (cat) in polymer stabilized liquid crystals Sniaricerche S.C.P.A. (IT) 1997-10-29 EP disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
EP-0656927-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX Sniaricerche S.C.P.A. (IT) 1995-06-14 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed