Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068084 | 0.95 | SYK (0.38) | SYKCCNT1IDH1USP30MET | |
| SCHEMBL24574434 | 0.92 | CCNT1 (0.43) | SYKCCNT1IDH1USP30MET | |
| SCHEMBL24574149 | 0.89 | FLT3 (0.48) | SYKCCNT1IDH1USP30FLT3 | |
| SCHEMBL24231691 | 0.89 | SYK (0.43) | SYKCCNT1IDH1USP30MET | |
| SCHEMBL24574384 | 0.86 | USP30 (0.37) | SYKCCNT1USP30PIK3CDFLT3 | |
| SCHEMBL24977595 | 0.85 | HDAC4 (0.38) | SYKCCNT1IDH1USP30FLT3 | |
| SCHEMBL24977598 | 0.85 | HDAC4 (0.38) | SYKCCNT1IDH1USP30FLT3 | |
| SCHEMBL24975718 | 0.81 | MAPK9 (0.42) | IDH1USP30HDAC4HDAC6BTK | |
| SCHEMBL24975716 | 0.81 | MAPK9 (0.42) | IDH1USP30HDAC4HDAC6BTK | |
| SCHEMBL30248414 | 0.81 | MAPK9 (0.42) | IDH1USP30HDAC4HDAC6BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140647-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2022-06-30 | — | — | WO | disclosed |