SCHEMBL24574875

SCHEMBL24574875

CC(C)c1cccc(C(C)C)c1NC(=O)N(C)C(C)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MTOR P42345 1/20 0.66
KMT2A Q03164 2/20 0.55
LMNA P02545 1/20 0.55
MEN1 O00255 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ROCK2 O75116 2/20 0.47
ROCK1 Q13464 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24575748 0.93 MTOR (0.58) MTORKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL20568008 0.84 MTOR (0.68) MTORLMNASMN1; SMN2ROCK2ROCK1
SCHEMBL22414240 0.84 MTOR (0.68) MTORLMNASMN1; SMN2ROCK2ROCK1
SCHEMBL24777791 0.80 MTOR (1.00) MTORROCK2ROCK1
SCHEMBL20540474 0.79 KMT2A (0.57) KMT2ALMNAMEN1SMN1; SMN2
SCHEMBL22414244 0.78 MTOR (0.59) MTORROCK2ROCK1
SCHEMBL24575427 0.77 MTOR (0.46) MTORKMT2ALMNAMEN1SMN1; SMN2
SCHEMBL22414276 0.75 MTOR (0.82) MTORSMN1; SMN2ROCK2ROCK1
SCHEMBL22414278 0.74 MTOR (0.54) MTORKMT2AMEN1SMN1; SMN2ROCK2
SCHEMBL855911 0.73 LMNA (0.48) KMT2ALMNAMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795315-B2 Group 5 metal complexes for producing amine-functionalized polyolefins THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-10-24 US disclosed
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed
WO-2022133594-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-30 WO disclosed