Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.67 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | KDM6B | O15054 | 4/20 | 0.43 |
| ▸ | KDM4A | O75164 | 4/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.43 |
| ▸ | HIF1AN | Q9NWT6 | 4/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.43 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694286 | 0.87 | EGLN1 (0.62) | EGLN1CYP2C8EGLN2EGLN3DHODH | |
| SCHEMBL3523901 | 0.75 | NPY5R (0.55) | — | |
| SCHEMBL11422025 | 0.75 | PIN1 (0.62) | KDM6BKDM4AKDM4DHIF1ANKDM2A | |
| SCHEMBL24575031 | 0.73 | EGLN1 (1.00) | EGLN1CYP2C8EGLN2EGLN3 | |
| SCHEMBL4770414 | 0.73 | NPY5R (0.49) | KDM6BKDM4AKDM4DHIF1ANKDM2A | |
| SCHEMBL4058072 | 0.70 | DHODH (0.51) | EGLN1DHODH | |
| SCHEMBL29694398 | 0.70 | DHODH (0.45) | EGLN1CYP2C8EGLN2EGLN3KDM6B | |
| SCHEMBL932031 | 0.70 | DHODH (0.45) | EGLN1CYP2C8EGLN2EGLN3KDM6B | |
| SCHEMBL10983615 | 0.69 | EGLN1 (0.40) | EGLN1CYP2C8EGLN2EGLN3KDM6B | |
| SCHEMBL1298745 | 0.69 | DHODH (0.59) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136206-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-30 | — | — | WO | disclosed |