SCHEMBL2457569

SCHEMBL2457569

N#Cc1c(F)c(Sc2cc(Cl)ccc2Cl)c(Sc2cc(Cl)ccc2Cl)c(Nc2ccccc2)c1C#N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.37
IDO1 P14902 1/20 0.33
CXCR2 P25025 1/20 0.33
ADORA1 P30542 4/20 0.32
ALDH1A1 P00352 3/20 0.32
ADORA2B P29275 2/20 0.32
HPGD P15428 1/20 0.32
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31
LDHA P00338 1/20 0.31
PLA2G1B P04054 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
MAP2K1 Q02750 1/20 0.31
MET P08581 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2453567 0.88 ADORA2A (0.38) ADORA2AIDO1CXCR2ADORA1ALDH1A1
SCHEMBL2451807 0.88 HSD11B1 (0.36) ADORA2ACXCR2ADORA1ALDH1A1ADORA2B
SCHEMBL2454939 0.84 MAP3K8 (0.36) ALDH1A1HPGDPLA2G1BATMNPSR1
SCHEMBL2458100 0.81 HSD11B1 (0.36) ADORA2ACXCR2ADORA1ALDH1A1ADORA2B
SCHEMBL2453615 0.79 ADORA1 (0.37) ADORA2ACXCR2ADORA1ALDH1A1ADORA2B
SCHEMBL2454063 0.77 CYP1A2 (0.34) PLA2G1BATMNPSR1ATG4B
SCHEMBL2456519 0.76 HSD11B1 (0.37) ADORA2ACXCR2ADORA1ALDH1A1NPSR1
SCHEMBL2452182 0.73 ADORA1 (0.35) ADORA2AADORA1ALDH1A1ADORA2BPLA2G1B
SCHEMBL7866675 0.73 ITGB2 (0.44) ALDH1A1HPGDFNTATAS1R3TAS1R1
SCHEMBL27622769 0.73 ADORA2A (0.39) ADORA2ACXCR2ADORA1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1577350-B1 Method for production of halogen-containing phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2011-09-14 EP disclosed
US-7473777-B2 Method for production of halogen-containing phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 2009-01-06 US disclosed
EP-1577350-A1 Method for production of halogen-containing phthalocyanine compound Nippon Shokubai Co., Ltd. (JP) 2005-09-21 EP disclosed
US-20050203293-A1 Method for production of halogen-containing phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 2005-09-15 US disclosed