SCHEMBL245777

SCHEMBL245777

C=C(C)C(=O)ONC(=O)C(CCC)CCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.44
CNR2 P34972 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
KDM4E B2RXH2 2/20 0.44
SOAT1 P35610 1/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245905 0.96 CNR2 (0.43) CNR1CNR2TRPV1SOAT1MEN1
SCHEMBL245170 0.96 CNR2 (0.43) CNR1CNR2TRPV1SOAT1MEN1
SCHEMBL245235 0.96 CNR2 (0.43) CNR1CNR2TRPV1SOAT1MEN1
SCHEMBL244581 0.94 ALDH1A1 (0.40) CNR1CNR2TRPV1KDM4ESOAT1
SCHEMBL243444 0.93 CNR1 (0.44) CNR1CNR2TRPV1KDM4ESOAT1
SCHEMBL244615 0.89 CNR2 (0.43) CNR1CNR2TRPV1SOAT1MEN1
SCHEMBL244705 0.89 CNR2 (0.43) CNR1CNR2TRPV1SOAT1MEN1
SCHEMBL244515 0.89 CNR2 (0.43) CNR1CNR2TRPV1SOAT1MEN1
SCHEMBL244707 0.89 TSHR (0.49)
SCHEMBL245108 0.89 TSHR (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9221738-B2 Method and system for purifying monomers EVONIK RÖHM GMBH (DE) 2015-12-29 US disclosed
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
US-20120065322-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT EVONIK ROEHM GMBH (DE) 2012-03-15 US disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
US-20120000764-A1 METHOD AND SYSTEM FOR PURIFYING MONOMERS EVONIK DEGUSSA GMBH (DE) 2012-01-05 US disclosed
US-20110318595-A1 COATING COMPOSITION, (METH)ACRYLIC POLYMER AND MONOMER MIXTURE FOR PRODUCING THE (METH)ACRYLIC POLYMER EVONIK ROEHM GMBH (DE) 2011-12-29 US disclosed
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2011-06-16 US disclosed
US-20110136975-A1 MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING EVONIK ROEHM GMBH (DE) 2011-06-09 US disclosed
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed
US-20110039977-A1 AQUEOUS DISPERSIONS COMPRISING AT LEAST ONE ALKYD RESIN EVONIK ROEHM GMBH (DE) 2011-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD DNMT1, TET1, MGMT CNR1 2078/4885CNR2 2367/4885TRPV1 4601/4885
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT MGMT, DNMT1, TET1 CNR1 589/4885CNR2 978/4885TRPV1 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.