Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 15/20 | 0.57 |
| ▸ | CA9 | Q16790 | 13/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577995 | 0.89 | HDAC1 (0.70) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL24579650 | 0.89 | HDAC1 (0.57) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL24579674 | 0.81 | HDAC1 (0.80) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL30527996 | 0.75 | CA12 (1.00) | HDAC1CA12CA9CA1CA2 | |
| SCHEMBL1172438 | 0.75 | CA12 (1.00) | HDAC1CA12CA9CA1CA2 | |
| SCHEMBL3940608 | 0.74 | CA12 (0.76) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL31752672 | 0.74 | CA12 (0.70) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL24579678 | 0.74 | HDAC1 (0.76) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL31455596 | 0.72 | CA12 (0.80) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL31455548 | 0.70 | CA12 (1.00) | CA12CA9CA1CA2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |