Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.76 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.76 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 10/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24579674 | 0.88 | HDAC1 (0.80) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL24579650 | 0.82 | HDAC1 (0.57) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL24579824 | 0.75 | HDAC1 (0.75) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL8033863 | 0.75 | GAA (0.57) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL6625089 | 0.75 | GABRA1 (0.49) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL28565657 | 0.75 | GABRA1 (0.49) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL24579653 | 0.74 | HDAC1 (0.60) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL16302105 | 0.74 | CA12 (0.68) | HDAC1HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL13606248 | 0.73 | HDAC1 (0.74) | HDAC1GAAKMT2ACA12CA9 | |
| SCHEMBL1172438 | 0.73 | CA12 (1.00) | HDAC1GAAKMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |