SCHEMBL24580348

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CCC[C@H]1C(=O)OC(c1ccccc1)(c1ccc(C2CCCCCCCCC2)cc1)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	PRCP	P42785	1/20	0.42

▸	ITGB3	P05106	4/20	0.41

▸	ITGA2B	P08514	4/20	0.41

▸	TLR2	O60603	1/20	0.41

▸	TLR1	Q15399	1/20	0.41

▸	MDM2	Q00987	1/20	0.37

▸	TGM2	P21980	4/20	0.36

▸	F13A1	P00488	2/20	0.36

▸	TGM1	P22735	2/20	0.36

▸	NPC1L1	Q9UHC9	1/20	0.35

▸	TGM6	O95932	1/20	0.34

▸	MDM4	O15151	1/20	0.34

▸	TP53	P04637	1/20	0.34

▸	F2	P00734	1/20	0.34

▸	PRSS1	P07477	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24580397	0.93	PRCP (0.37)	PRCPITGB3ITGA2BTLR2TLR1
SCHEMBL29696622	0.89	PRCP (0.49)	PRCPITGB3ITGA2BTLR2TLR1
SCHEMBL24579230	0.87	PRCP (0.39)	PRCP
SCHEMBL24828861	0.85	PRCP (0.39)	PRCPMDM2MDM4TP53
SCHEMBL22388726	0.85	PRCP (0.39)	PRCPMDM2MDM4TP53
SCHEMBL22388727	0.85	PRCP (0.39)	PRCPMDM2MDM4TP53
SCHEMBL15960070	0.82	PRCP (0.51)	PRCPITGB3ITGA2BTLR2TLR1
SCHEMBL30640764	0.82	PRCP (0.51)	PRCPITGB3ITGA2BTLR2TLR1
SCHEMBL29696668	0.82	PRCP (0.51)	PRCPITGB3ITGA2BTLR2TLR1
SCHEMBL24579905	0.81	FABP7 (0.37)	F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022138891-A1	METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE	中外製薬株式会社	2022-06-30	—	—	WO	disclosed