Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922253 | 0.76 | — | — | |
| SCHEMBL919995 | 0.73 | ALDH1A1 (0.33) | DPP4ALDH1A1KMT2A | |
| SCHEMBL389839 | 0.73 | — | — | |
| SCHEMBL922357 | 0.73 | — | — | |
| SCHEMBL30403656 | 0.71 | — | — | |
| SCHEMBL920527 | 0.70 | ALDH1A1 (0.37) | DPP4NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL10638201 | 0.70 | — | — | |
| SCHEMBL700807 | 0.69 | — | — | |
| SCHEMBL5594282 | 0.69 | ALDH1A1 (0.36) | NPC1RAB9ATSHRKDM4EMEN1 | |
| SCHEMBL28484470 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2018-09-25 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3020709-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORPORATION (US) | 2016-05-18 | — | — | EP | disclosed |
| EP-2542538-B1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2015-12-30 | — | — | EP | disclosed |
| US-20150203457-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| US-8969554-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| EP-2542538-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | DDT, AADAC, DAZAP1 | DPP4 22/4885HPGD 2935/4885NPC1 4693/4885 |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | DPP4 22/4885HPGD 2935/4885NPC1 4693/4885 |
| US-20150203457-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | DPP4 22/4885HPGD 2935/4885NPC1 4693/4885 |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | CBR3, DDT, CBR1 | DPP4 487/4885HPGD 4045/4885NPC1 4678/4885 |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | DPP4 22/4885HPGD 2935/4885NPC1 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.