Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12248328 | 0.79 | POLB (0.38) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL14521484 | 0.79 | TSHR (0.45) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL12438066 | 0.76 | USP2 (0.44) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL14077043 | 0.76 | KMT2A (0.43) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL24811359 | 0.76 | TSHR (0.42) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL25791501 | 0.76 | TSHR (0.47) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL12633370 | 0.74 | ALDH1A1 (0.58) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL12607684 | 0.72 | POLB (0.41) | TSHRPOLBGFERKMT2ACYP2C19 | |
| SCHEMBL20346222 | 0.72 | KMT2A (0.49) | TSHRKMT2ACYP2C19CYP2D6CYP2C9 | |
| SCHEMBL12131751 | 0.72 | USP2 (0.55) | TSHRPOLBGFERKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2022135332-A1 | STEROID CONJUGATE | 映恩生物制药（苏州）有限公司 | 2022-06-30 | — | — | WO | disclosed |