SCHEMBL24582

SCHEMBL24582

[c]1ccc2cnc3ccccc3c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.62
GPR3 P46089 3/20 0.62
TOP2A P11388 1/20 0.41
ADORA3 P0DMS8 1/20 0.38
PDPK1 O15530 1/20 0.37
CYP1A2 P05177 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CYP3A4 P08684 1/20 0.36
ERN1 O75460 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
GLA P06280 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26265 0.85 KDM4E (0.62) KDM4EGPR3TOP2AADORA3PDPK1
SCHEMBL24813 0.85 KDM4E (0.62) KDM4EGPR3TOP2AADORA3PDPK1
SCHEMBL24858 0.81 GPR3 (0.62) KDM4EGPR3TOP2AADORA3CYP1A2
Phenanthridine SCHEMBL31326572 0.78 KDM4E (0.91) KDM4EGPR3TOP2AADORA3PDPK1
Phenanthridine SCHEMBL8666 0.78 GPR3 (1.00) KDM4EGPR3TOP2AADORA3PDPK1
Phenanthridine SCHEMBL9106884 0.78 GPR3 (1.00) KDM4EGPR3TOP2AADORA3PDPK1
Phenanthridine SCHEMBL30823553 0.78 GPR3 (1.00) KDM4EGPR3TOP2AADORA3PDPK1
Phenanthridine SCHEMBL30914262 0.78 GPR3 (1.00) KDM4EGPR3TOP2AADORA3PDPK1
SCHEMBL9479132 0.76 CYP3A4 (0.61) KDM4ECYP1A2CYP3A4ERN1MAPT
Phenanthridine SCHEMBL23003530 0.76 GPR3 (0.95) KDM4EGPR3TOP2AADORA3PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2080 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
CN-107586290-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-05-11 CN claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-108493343-B Perovskite film, preparation method thereof and application of film in photoelectric device 清华大学 2020-04-24 CN claimed
CN-109309163-B Organic electroluminescent device 清华大学 2019-12-17 CN claimed
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US claimed
US-20040110756-A1 New anthracene derivatives and their use as pharmaceutical preparations ZENTARIS GMBH (DE) 2004-06-10 US claimed
US-20040097530-A1 Novel heteroaryl derivatives and their use as medicaments ZENTARIS AG (DE) 2004-05-20 US claimed
US-6706722-B2 IN PARTICULAR FOR TREATING TUMORS. ZENTARIS AG (DE) 2004-03-16 US claimed
US-6638935-B2 Antitumor agents ZENTARIS AG (DE) 2003-10-28 US claimed
CN-1447796-A Novel heteroaryl derivatives and their use as medicaments ZENTARIS AG (DE) 2003-10-08 CN claimed
CN-1443171-A Novel heteroaryl derivatives and use thereof as pharmaceuticals ZENTARIS AG (DE) 2003-09-17 CN claimed
CN-1443172-A Novel heteroaryl derivatives and their use as medicaments ZENTARIS AG (DE) 2003-09-17 CN claimed
US-20020132821-A1 Novel heteroaryl derivatives and their use as medicaments ZENTARIS GMBH (DE) 2002-09-19 US claimed
US-20020111354-A1 Novel heteroary1 derivatives and their use as medicaments ZENTARIS GMBH (DE) 2002-08-15 US claimed
US-20020103214-A1 Novel heteroaryl derivatives and their use as medicaments ZENTARIS GMBH (DE) 2002-08-01 US claimed