Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.76 |
| ▸ | ABL1 | P00519 | 5/20 | 0.76 |
| ▸ | ABL2 | P42684 | 5/20 | 0.76 |
| ▸ | PRKCA | P17252 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459209 | 0.87 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2461152 | 0.86 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2461249 | 0.86 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2461344 | 0.83 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2460994 | 0.80 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2458392 | 0.80 | EGFR (0.78) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2461138 | 0.80 | EGFR (0.70) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2463632 | 0.79 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2461133 | 0.79 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR | |
| SCHEMBL2461158 | 0.79 | EGFR (1.00) | EGFRABL1ABL2PRKCAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041137-B1 | PYRROLOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2011-09-28 | — | — | EP | claimed |
| EP-2041137-B1 | PYRROLOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2011-09-28 | — | — | EP | disclosed |