Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293051 | 0.95 | PARP10 (0.66) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6289863 | 0.93 | PARP10 (0.63) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6290343 | 0.91 | PARP10 (0.61) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6293879 | 0.91 | PARP10 (0.61) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6293904 | 0.91 | PARP10 (0.61) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6290746 | 0.88 | PARP10 (0.59) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6290371 | 0.88 | PARP10 (0.59) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL702582 | 0.88 | PARP10 (0.58) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| SCHEMBL6290676 | 0.87 | ALDH1A1 (0.61) | PARP10ALDH1A1L3MBTL1LMNAHTR1A | |
| Ammonia Solution, Strong SCHEMBL4266595 | 0.86 | PARP10 (0.56) | PARP10ALDH1A1L3MBTL1LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481327-B2 | Methods for using congeneric, chlorinated, brominated and/or iodised, fluorinated aromatic standard compounds having two benzol rings | CHIRON AS (NO) | 2013-07-09 | — | — | US | disclosed |
| US-20110229973-A1 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2011-09-22 | — | — | US | disclosed |
| US-20070298501-A1 | Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof | CHIRON AS (NO) | 2007-12-27 | — | — | US | disclosed |
| WO-2005077868-A2 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2005-08-25 | — | — | WO | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| US-4278816-A | FROM DIPHENYL ETHERS AND HYDROGEN SULFIDE, ABSORPTIVE CATALYST | STAUFFER CHEMICAL COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |
| US-3939084-A | Functional fluid compositions containing substituted pyrimidines | MONSANTO COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298501-A1 | Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof | CBR1, CYP1A1, CYP1B1 | PARP10 3569/4885ALDH1A1 1513/4885L3MBTL1 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.