SCHEMBL24585705

SCHEMBL24585705

c1ccc(-c2cc3c4ccc(N(c5ccccc5)c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)cc4oc3c3ccccc23)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.32
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24585300 0.95 DYRK1A (0.31) DYRK1A
SCHEMBL24585506 0.95 DYRK1A (0.34) DYRK1AMEN1THRBRECQLBLM
SCHEMBL24585723 0.94 ALOX5 (0.31) DYRK1A
SCHEMBL24585508 0.92 DYRK1A (0.30) DYRK1A
SCHEMBL9916406 0.92 ALOX5 (0.35)
SCHEMBL24586262 0.92 CYP1A1 (0.31)
SCHEMBL24585509 0.91 CYP1A1 (0.31)
SCHEMBL24585299 0.90 DYRK1A (0.32) DYRK1A
SCHEMBL26550821 0.89 ALOX5 (0.41) MEN1THRBRECQLBLMKMT2A
SCHEMBL24585405 0.89 PRKDC (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4019505-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME, METHOD FOR MANUFACTURING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE LT Materials Co., Ltd. (KR) 2022-06-29 EP disclosed
US-9598411-B2 Substituted benzimidazole-type piperidine compounds and uses thereof PURDUE PHARMA L.P. (US) 2017-03-21 US disclosed