SCHEMBL24586405

SCHEMBL24586405

c1ccc(-c2cc(-c3ccc(-c4nc(-c5ccccc5)cc(-c5ccccc5)n4)cc3)c3c(c2)oc2cc4ccccc4cc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.42
KMT2A Q03164 7/20 0.42
ALDH1A1 P00352 6/20 0.42
MAPT P10636 6/20 0.42
HPGD P15428 6/20 0.42
NTSR1 P30989 1/20 0.42
KDM4E B2RXH2 4/20 0.38
LMNA P02545 2/20 0.38
GLA P06280 1/20 0.38
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
CYP2C19 P33261 2/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24066159 1.00 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24066256 1.00 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL25666503 1.00 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24066271 0.94 ALDH1A1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24066261 0.94 ALDH1A1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24542444 0.94 ALDH1A1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24066257 0.94 ALDH1A1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24585736 0.92 CYP1A1 (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL29298591 0.91 ALDH1A1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24585517 0.91 CYP1A1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189645-A1 ORGANIC LIGHT-EMITTING DEVICE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189645-A1 ORGANIC LIGHT-EMITTING DEVICE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-06-15 US disclosed
EP-4019505-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME, METHOD FOR MANUFACTURING THE SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT EMITTING DEVICE LT Materials Co., Ltd. (KR) 2022-06-29 EP disclosed