Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 14/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920031 | 0.85 | CCR2 (0.50) | CCR2ADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL28829848 | 0.81 | CCR2 (0.51) | CCR2MCL1KDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL27999948 | 0.80 | CCR2 (0.50) | CCR2MCL1KDM4EALDH1A1GLA | |
| SCHEMBL9011812 | 0.79 | CCR2 (0.56) | CCR2KDM4EALDH1A1 | |
| SCHEMBL9934119 | 0.78 | CCR2 (1.00) | CCR2 | |
| SCHEMBL28141029 | 0.78 | CCR2 (0.55) | CCR2ADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL1625796 | 0.75 | CCR2 (0.51) | CCR2MCL1TRPV4 | |
| SCHEMBL9933800 | 0.75 | CCR2 (1.00) | CCR2 | |
| SCHEMBL19336476 | 0.74 | CCR2 (0.86) | CCR2 | |
| Hydrochloric Acid SCHEMBL27999955 | 0.74 | CNR1 (0.47) | CCR2MCL1KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |