Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | VEGFA | P15692 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | S100A9 | P06702 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26694042 | 0.84 | TRPV4 (0.44) | HTTSMOKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29837763 | 0.84 | TRPV4 (0.44) | HTTSMOKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31326177 | 0.78 | HTT (0.38) | HTTSMOKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24588149 | 0.76 | S100A9 (0.40) | S100A9CYP11B1CYP11B2TRPV4 | |
| SCHEMBL25347280 | 0.75 | LRRK2 (0.37) | HTTSMOKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31326212 | 0.75 | LRRK2 (0.37) | HTTSMOKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31326191 | 0.73 | S100A9 (0.36) | HTTKDM4EALDH1A1L3MBTL1HPGDS | |
| SCHEMBL30624366 | 0.72 | HTT (0.44) | HTTKDM4EALDH1A1L3MBTL1HPGDS | |
| SCHEMBL846133 | 0.72 | HTT (0.44) | HTTKDM4EALDH1A1L3MBTL1HPGDS | |
| SCHEMBL25239312 | 0.72 | CYP11B1 (0.37) | HTTSMOKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |