Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 14/20 | 0.59 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.59 |
| ▸ | CDK2 | P24941 | 7/20 | 0.59 |
| ▸ | CDK9 | P50750 | 7/20 | 0.59 |
| ▸ | CDK7 | P50613 | 8/20 | 0.41 |
| ▸ | CCNH | P51946 | 8/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046133 | 0.79 | CCNK (0.83) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30456540 | 0.78 | CCNK (0.72) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25364470 | 0.78 | CCNK (0.72) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25597596 | 0.78 | CCNK (0.60) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21188433 | 0.76 | CDK5 (0.38) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL20846353 | 0.76 | CDK2 (0.48) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24839545 | 0.75 | CCNK (1.00) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24588737 | 0.75 | CCNK (1.00) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30204070 | 0.75 | CCNK (1.00) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24583273 | 0.75 | PIK3CA (0.43) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269403-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | GT Apeiron Therapeutics Limited (HK) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |