Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590922 | 0.93 | HDAC4 (0.44) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL19943418 | 0.92 | HDAC4 (0.40) | HDAC4HDAC1 | |
| SCHEMBL19978557 | 0.92 | HDAC4 (0.40) | HDAC4HDAC1 | |
| SCHEMBL21650049 | 0.92 | HDAC4 (0.40) | HDAC4HDAC1 | |
| SCHEMBL20611590 | 0.90 | HDAC4 (0.45) | HDAC4HDAC1 | |
| SCHEMBL20611440 | 0.90 | HDAC4 (0.45) | HDAC4HDAC1 | |
| SCHEMBL20611641 | 0.90 | HDAC4 (0.45) | HDAC4HDAC1 | |
| SCHEMBL19819244 | 0.90 | HDAC4 (0.45) | HDAC4HDAC1 | |
| SCHEMBL19943521 | 0.90 | HDAC4 (0.45) | HDAC4HDAC1 | |
| SCHEMBL19943404 | 0.90 | HDAC4 (0.45) | HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265083-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2022-07-06 | — | — | EP | disclosed |