Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320669 | 0.82 | TDP1 (0.58) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL11989021 | 0.80 | TDP1 (0.55) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL3341020 | 0.80 | TDP1 (0.67) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL20687292 | 0.79 | TDP1 (0.46) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL29617414 | 0.79 | TDP1 (0.55) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL11052379 | 0.79 | TDP1 (0.65) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL29617409 | 0.79 | TDP1 (0.55) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL605531 | 0.78 | TDP1 (0.53) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL12138378 | 0.78 | TDP1 (0.53) | TDP1MEN1GAAKMT2AEPHX1 | |
| SCHEMBL605532 | 0.78 | TDP1 (0.59) | TDP1MEN1GAAKMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512851-B1 | BETA-LACTAMASE INHIBITOR COMPOUNDS | ENTASIS THERAPEUTICS LTD (GB) | 2022-07-06 | — | — | EP | disclosed |