Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.45 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617414 | 0.88 | TDP1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL320669 | 0.83 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3341020 | 0.83 | TDP1 (0.67) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL29617412 | 0.82 | TDP1 (0.61) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL27183994 | 0.82 | TDP1 (0.61) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL11052379 | 0.80 | TDP1 (0.65) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL30759450 | 0.79 | TDP1 (0.52) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL24594841 | 0.79 | TDP1 (0.52) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3020258 | 0.79 | TDP1 (0.81) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL569251 | 0.79 | TDP1 (0.74) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12576051-B2 | Methods and composition for treating respiratory obstructive diseases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-17 | — | — | US | disclosed |
| US-12391643-B2 | Substituted amino-thiol and amino-disulfide compounds, and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-08-19 | — | — | US | disclosed |
| CN-113613642-B | Substituted amino-thiol and amino-disulfide compounds and uses thereof | 加利福尼亚大学董事会 | 2024-08-06 | — | — | CN | disclosed |
| US-20220265583-A1 | METHODS AND COMPOSITION FOR TREATING RESPIRATORY OBSTRUCTIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-08-25 | — | — | US | disclosed |
| US-20220135524-A1 | SUBSTITUTED AMINO-THIOL AND AMINO-DISULFIDE COMPOUNDS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391643-B2 | Substituted amino-thiol and amino-disulfide compounds, and uses thereof | FABP1, CBS, CTH | TDP1 2952/4885MEN1 3652/4885GAA 2219/4885 |
| US-20220265583-A1 | METHODS AND COMPOSITION FOR TREATING RESPIRATORY OBSTRUCTIVE DISEASES | COX6C, CKMT1A; CKMT1B, MT-CO2 | TDP1 3164/4885MEN1 4856/4885GAA 452/4885 |
| US-20220135524-A1 | SUBSTITUTED AMINO-THIOL AND AMINO-DISULFIDE COMPOUNDS, AND USES THEREOF | FABP1, CBS, CTH | TDP1 2952/4885MEN1 3652/4885GAA 2219/4885 |
| US-12576051-B2 | Methods and composition for treating respiratory obstructive diseases | CFTR, CCR10, SLC26A4 | TDP1 4301/4885MEN1 4871/4885GAA 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.