Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 12/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748960 | 0.82 | KDM5A (0.37) | KDM5AKDM5B | |
| SCHEMBL20314862 | 0.80 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL21937398 | 0.76 | MAPT (0.34) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL21736809 | 0.76 | KDM5A (0.36) | KDM5A | |
| SCHEMBL7215529 | 0.76 | KDM5A (0.39) | KDM5AMAPK1RIPK1CCNCCDK8 | |
| SCHEMBL10058048 | 0.76 | MEN1 (0.38) | KDM5AMAPK1RIPK1CCNCCDK8 | |
| SCHEMBL21736808 | 0.74 | KDM5A (0.33) | KDM5A | |
| SCHEMBL19779742 | 0.74 | CYP2E1 (0.37) | KDM5AMAPK1RIPK1CCNCCDK8 | |
| SCHEMBL13747989 | 0.74 | CYP11B2 (0.35) | KDM5A | |
| SCHEMBL24595067 | 0.74 | KDM5A (0.35) | KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636636-B1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | MITSUI CHEMICALS AGRO INC (JP) | 2022-07-06 | — | — | EP | disclosed |