Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877062 | 0.86 | MAPK1 (0.61) | SMN1; SMN2KMT2AMAPK1TSHRRAB9A | |
| SCHEMBL1030124 | 0.84 | PI4KB (0.50) | SMN1; SMN2KMT2AMAPK1TSHRRAB9A | |
| SCHEMBL12368644 | 0.84 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AMAPK1TSHRRAB9A | |
| SCHEMBL3933173 | 0.83 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AMAPK1RAB9ANPC1 | |
| SCHEMBL465934 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AMAPK1RAB9ANPC1 | |
| SCHEMBL28320049 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMAPK1TSHRRAB9A | |
| SCHEMBL4875202 | 0.79 | AOC3 (0.55) | SMN1; SMN2KMT2ATSHRRAB9ANPC1 | |
| SCHEMBL6841098 | 0.77 | MAPT (0.62) | SMN1; SMN2PKMRAB9ANPC1HTT | |
| SCHEMBL4873516 | 0.77 | MAPK1 (0.56) | SMN1; SMN2KMT2AMAPK1RAB9ANPC1 | |
| SCHEMBL20935220 | 0.75 | PDE5A (0.66) | SMN1; SMN2KMT2AMAPK1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636636-B1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | MITSUI CHEMICALS AGRO INC (JP) | 2022-07-06 | — | — | EP | disclosed |