Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535545 | 0.85 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL24595685 | 0.82 | TP53 (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21524283 | 0.81 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18535547 | 0.76 | MIF (0.55) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL24595604 | 0.75 | GAPDH (0.46) | NPC1RAB9AGAPDHMAOBACHE | |
| SCHEMBL21116040 | 0.75 | MAOB (0.36) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL21116065 | 0.74 | MAOB (0.36) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18535449 | 0.73 | MAOB (0.35) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18583386 | 0.73 | MAOB (0.36) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18535455 | 0.73 | MAOB (0.34) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327779-A2 | SYSTEM AND METHOD | AMO Ireland (IE) | 2024-02-28 | — | — | EP | disclosed |
| EP-3958788-B1 | SYSTEM AND METHOD | AMO Ireland (IE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |