Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583698 | 0.88 | STS (0.48) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24595695 | 0.86 | STS (0.48) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24595690 | 0.84 | STS (0.40) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL23713500 | 0.79 | STS (0.51) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL18583392 | 0.78 | NPC1 (0.72) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24046224 | 0.78 | NPC1 (0.70) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9607852 | 0.78 | RAB9A (0.63) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL22625376 | 0.77 | RXFP1 (0.59) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL18535585 | 0.77 | NPC1 (0.37) | STSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21587890 | 0.76 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |