Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 16/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596196 | 0.92 | MAT2A (0.57) | MAT2AALDH1A1ALDH1A3CYP2D6CYP2C19 | |
| SCHEMBL29789989 | 0.81 | MAT2A (0.57) | MAT2A | |
| SCHEMBL24596306 | 0.81 | MAT2A (0.57) | MAT2A | |
| SCHEMBL24596198 | 0.81 | MAT2A (0.57) | MAT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL24596193 | 0.80 | MAT2A (0.61) | MAT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL29789928 | 0.79 | MAT2A (0.57) | MAT2A | |
| SCHEMBL24596308 | 0.79 | MAT2A (0.57) | MAT2A | |
| SCHEMBL24596203 | 0.77 | MAT2A (0.73) | MAT2A | |
| SCHEMBL24596312 | 0.77 | MAT2A (0.58) | MAT2AALDH1A1 | |
| SCHEMBL29789853 | 0.77 | MAT2A (0.55) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273146-A1 | TRICYCLIC COMPOUND AND USE THEREOF | Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |