Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.72 |
| ▸ | HRH1 | P35367 | 7/20 | 0.72 |
| ▸ | DRD3 | P35462 | 7/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.61 |
| ▸ | HTR2A | P28223 | 5/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.61 |
| ▸ | DRD1 | P21728 | 5/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.61 |
| ▸ | HTR2B | P41595 | 4/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677919 | 0.92 | DRD2 (0.61) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL23898817 | 0.91 | DRD2 (0.74) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL9677473 | 0.90 | HRH1 (0.58) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL6966810 | 0.87 | DRD2 (0.75) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL9678658 | 0.86 | DRD2 (0.55) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL9676477 | 0.86 | DRD2 (0.65) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL9678544 | 0.86 | DRD2 (0.55) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL9676172 | 0.86 | DRD2 (0.55) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL6969678 | 0.86 | DRD2 (0.74) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL25918374 | 0.86 | DRD2 (0.67) | DRD2HRH1DRD3CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146970-A1 | METHODS OF METABOLIZING METOPIMAZINE AND ITS SALTS | NEUROGASTRX, INC. (US) | 2022-07-07 | — | — | WO | disclosed |