SCHEMBL24596807

SCHEMBL24596807

Cc1c(C(=O)Nc2ccc(S(C)(=O)=O)c(F)c2)cn(CCCCCO)c1-c1ccccc1C(F)(F)F

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 2/20 0.67
S1PR1 P21453 13/20 0.40
PTPRC P08575 1/20 0.38
PTGES O14684 1/20 0.38
S1PR3 Q99500 5/20 0.38
TRPV4 Q9HBA0 1/20 0.37
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379459 0.94 NR3C2 (0.77) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL23275830 0.94 NR3C2 (0.77) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL29410842 0.94 NR3C2 (0.77) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL1380002 0.87 NR3C2 (0.88) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL23275819 0.85 NR3C2 (0.59) NR3C2S1PR1PTPRCS1PR3TRPV4
SCHEMBL12296563 0.85 NR3C2 (0.75) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL1378883 0.84 NR3C2 (0.90) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL23275799 0.84 NR3C2 (0.58) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL29410833 0.84 NR3C2 (0.58) NR3C2S1PR1PTPRCPTGESS1PR3
SCHEMBL23287494 0.83 NR3C2 (0.56) NR3C2S1PR1PTPRCPTGESS1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220211665-A1 PYRROLE AMIDE COMPOUND AND USE THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211665-A1 PYRROLE AMIDE COMPOUND AND USE THEREOF MC2R, NR3C2, AVPR2 NR3C2 2/4885S1PR1 582/4885PTPRC 3118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.