Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750605 | 1.00 | DDB1 (0.43) | DDB1CRBNGSPT1BRD4CREBBP | |
| SCHEMBL31028610 | 0.93 | DDB1 (0.43) | DDB1CRBNGSPT1BRD4CREBBP | |
| SCHEMBL31028650 | 0.85 | CRBN (0.41) | DDB1CRBNGSPT1 | |
| SCHEMBL31043085 | 0.82 | DDB1 (0.38) | DDB1CRBNGSPT1 | |
| SCHEMBL31043111 | 0.82 | DDB1 (0.40) | DDB1CRBNGSPT1 | |
| SCHEMBL30938923 | 0.81 | CRBN (0.42) | DDB1CRBN | |
| SCHEMBL31292089 | 0.81 | DDB1 (0.46) | DDB1CRBNGSPT1BRD4CREBBP | |
| SCHEMBL31028636 | 0.81 | CRBN (0.45) | DDB1CRBNGSPT1 | |
| SCHEMBL24597589 | 0.80 | CRBN (0.70) | DDB1CRBNGSPT1 | |
| SCHEMBL24745730 | 0.80 | CRBN (0.41) | DDB1CRBNGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022144416-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2022-07-07 | — | — | WO | disclosed |