SCHEMBL31028610

SCHEMBL31028610

Cc1nc2ccc(CNC(=O)OC(C)(C)C)cc2cc1C1CCC(=O)NC1=O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 15/20 0.43
▸ CRBN Q96SW2 15/20 0.43
▸ GSPT1 P15170 3/20 0.43
▸ BRD4 O60885 1/20 0.39
▸ CREBBP Q92793 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ IGF1R P08069 1/20 0.37
▸ GRM2 Q14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29750605 0.93 DDB1 (0.43) DDB1CRBNGSPT1BRD4CREBBP
SCHEMBL24597653 0.93 DDB1 (0.43) DDB1CRBNGSPT1BRD4CREBBP
SCHEMBL31043108 0.86 CRBN (0.42) DDB1CRBNGSPT1
SCHEMBL31028707 0.82 DDB1 (0.38) DDB1CRBNGSPT1
SCHEMBL31028597 0.81 DDB1 (0.40) DDB1CRBNGSPT1
SCHEMBL30938982 0.81 CRBN (0.42) DDB1CRBN
SCHEMBL31292089 0.81 DDB1 (0.46) DDB1CRBNGSPT1BRD4CREBBP
SCHEMBL31028651 0.81 CRBN (0.45) DDB1CRBNGSPT1
SCHEMBL24745595 0.80 CRBN (0.41) DDB1CRBNGSPT1
SCHEMBL24744925 0.79 GPR119 (0.41) DDB1CRBNL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662206-A1 GSPT1 DEGRADER COMPOUNDS Captor Therapeutics S.A. (PL) 2025-12-17 — — EP disclosed
WO-2024165577-A1 GSPT1 DEGRADER COMPOUNDS CAPTOR THERAPEUTICS S.A. (PL) 2024-08-15 — — WO disclosed
WO-2024167423-A1 GSPT1 DEGRADER COMPOUNDS CAPTOR THERAPEUTICS S.A. (PL) 2024-08-15 — — WO disclosed
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