Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996577 | 0.90 | ADORA3 (0.72) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29444504 | 0.90 | ADORA3 (0.72) | ADORA3ADORA2AADORA1 | |
| SCHEMBL22601498 | 0.90 | ADORA3 (0.72) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24500475 | 0.90 | ADORA3 (0.72) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24600921 | 0.90 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24600696 | 0.88 | ADORA3 (0.66) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13382559 | 0.86 | ADORA3 (0.76) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13238334 | 0.86 | PI4KA (0.65) | ADORA3ADORA2AADORA1 | |
| SCHEMBL20434974 | 0.85 | PI4KA (0.64) | ADORA3 | |
| SCHEMBL17824401 | 0.85 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273153-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |