Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601057 | 0.92 | ADORA3 (0.46) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24601009 | 0.86 | ADORA3 (0.57) | ADORA3ADORA2AADORA1MAPK1MAPT | |
| SCHEMBL24601008 | 0.86 | ADORA3 (0.57) | ADORA3ADORA2AADORA1MAPK1MAPT | |
| SCHEMBL24601526 | 0.86 | ADORA3 (0.57) | ADORA3ADORA2AADORA1MAPK1MAPT | |
| SCHEMBL14111376 | 0.83 | ADORA3 (0.56) | ADORA3ADORA2AADORA1LMNATHRB | |
| SCHEMBL24601058 | 0.82 | ADORA2A (0.37) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24601056 | 0.82 | ADORA2A (0.37) | ADORA3ADORA2AADORA1 | |
| SCHEMBL14111548 | 0.82 | ADORA3 (0.55) | ADORA3ADORA2AADORA1MAPK1MAPT | |
| SCHEMBL14086536 | 0.82 | ADORA3 (0.55) | ADORA3ADORA2AADORA1MAPK1MAPT | |
| SCHEMBL22757490 | 0.79 | ADORA3 (0.48) | ADORA3ADORA2AADORA1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |