Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601005 | 0.93 | ADORA3 (0.47) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL24600901 | 0.93 | ADORA2A (0.44) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL24601092 | 0.92 | KCNH2 (0.41) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL24601226 | 0.92 | ADORA3 (0.44) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL24601236 | 0.92 | ADORA3 (0.41) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL24600660 | 0.91 | ADORA3 (0.39) | ADORA2AADORA3ADORA1ADORA2BTSHR | |
| SCHEMBL24600701 | 0.91 | ADORA3 (0.41) | ADORA2AADORA3ADORA1ADORA2BTSHR | |
| SCHEMBL24600916 | 0.91 | KCNA5 (0.45) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL24601100 | 0.90 | NT5E (0.40) | ADORA2AADORA3ADORA1ADORA2BNT5E | |
| SCHEMBL30850586 | 0.88 | ADORA3 (0.56) | ADORA2AADORA3ADORA1ADORA2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |