Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 17/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | PPARD | Q03181 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601290 | 0.92 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AHTR2CPPARG | |
| SCHEMBL24600730 | 0.91 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AHTR2CPPARG | |
| SCHEMBL24600696 | 0.89 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL24600921 | 0.88 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AHTR2CPPARG | |
| SCHEMBL7103371 | 0.82 | ADORA3 (0.56) | ADORA3ADORA1ADORA2A | |
| SCHEMBL6835048 | 0.82 | ADORA3 (0.56) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22750498 | 0.82 | ADORA3 (0.68) | ADORA3ADORA1ADORA2AHTR2CPPARG | |
| SCHEMBL24600773 | 0.82 | NT5E (0.54) | ADORA3ADORA1ADORA2AHTR2CPPARG | |
| SCHEMBL13382559 | 0.81 | ADORA3 (0.76) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL19366691 | 0.81 | NT5E (0.57) | ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273153-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |